Mathematical modeling of the processes of formation of single-stranded damages of large size and their transformation into double-stranded discontinuities of cellular DNA
Date
2019-09-30
Authors
Knigavko, Volodymyr
Batyuk, Liliya
Zaytseva, Olga
Bondarenko, Maryna
Ponomarenko, Natalya
Rukin, Aleksei
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The theoretical investigation was shown that single-strand breaks are repaired by the mechanism of ultrafast reparations, and a significant number of them are repaired during irradiation, depending on the dose rate.
Description
Keywords
DNA polymerase, dose rate, ionizing radiation, one single-strand gap, mathematical modeling
Citation
Mathematical modeling of the processes of formation of single-stranded damages of large size and their transformation into double-stranded discontinuities of cellular DNA / V. G. Knigavko, L. V. Batyuk, O. V. Zaytseva, M. A. Bondarenko, N. S. Ponomarenko, A. S. Rukin // Медична та клінічна хімія. ‒ 2019. ‒ Т. 21, № 3 (80). – P. 33‒34.