Наукові роботи молодих вчених. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки
Permanent URI for this collectionhttps://repo.knmu.edu.ua/handle/123456789/1568
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Item Comprehensive pre-discharge symptoms assessment in hypertensive patients hospitalized for COVID-19 allows to predict persistence of symptoms at 3 months(2024) Honchar, Oleksii; Ashcheulova, TetianaItem Improved accuracy of long COVID-19 prediction in hospitalized hypertensive patients compared to the general cohort(2024) Honchar, Oleksii; Ashcheulova, TetianaItem Short-term echocardiographic follow-up after hospitalization for COVID-19: a focus on early post-acute changes(Frontiers Media S.A., 2023-11) Honchar, Oleksii; Ashcheulova, Tetiana; Гончарь, Олексій Володимирович; Ащеулова, Тетяна ВадимівнаBackground: Impaired physical functional status is one of the typical long-term sequelae of COVID-19 infection that significantly affects the quality of life and work capacity. Minor changes in cardiac structure and function that are unable to cause the manifestation of overt heart failure may remain undetected in COVID-19 convalescents, at the same time potentially contributing to the persistence of symptoms and development of long COVID syndrome. Purpose: To study the typical features and short-term dynamics of cardiac remodeling and possible signs of cardiac dysfunction following hospitalization for COVID-19. Methods: This is a combined cross-sectional and longitudinal cohort study in which 176 hospitalized patients (93 female and 83 male, mean age 53.4 ± 13.6 years) with COVID-19 infection underwent comprehensive transthoracic echocardiography pre-discharge (22.6 ± 7.1 days from the onset of symptoms) with repeated evaluation after 1 month. The control group included 88 age-, sex-, height- and weight-matched healthy individuals, with a subset of those (n = 53) matched to the subset of non-hypertensive study participants (n = 106). Results: Concentric left ventricular geometry was revealed in 59% of participants, including 43% of non-hypertensive subjects; predominantly Grade I diastolic dysfunction was found in 35 and 25% of patients, respectively. Other findings were naturally following from described phenotype of the left venticle and included a mild increase in the absolute and relative wall thickness (0.45 ± 0.07 vs. 0.39 ± 0.04, p < 0.001), worsening of diastolic indices (e’ velocity 9.2 ± 2.2 vs. 11.3 ± 2.6 cm/s, p < 0.001, E/e’ ratio 7.5 ± 1.8 vs. 6.8 ± 1.7, p = 0.002) and global longitudinal strain (17.5 ± 2.4 vs. 18.6 ± 2.2, p < 0.001). No significant improvement was found on re-evaluation at 1 month. Conclusions: Hospitalized patients recovering from COVID-19 were characterized by a high prevalence of left ventricular concentric remodeling, predominantly Grade I diastolic dysfunction, and a mild decrease in the longitudinal systolic function. These changes were less frequent but still prevalent in the non-hypertensive subgroup and largely persisted throughout the 1-month follow-up.Item Структурно-функціональне ремоделювання серця у хворих на гіпертонічну хворобу та COVID-19: оцінка змін наприкінці періоду госпіталізації та упродовж 1 місяця спостереження(Всеукраїнська асоціація кардіологів України, 2023) Гончарь, Олексій Володимирович; Honchar, OleksiiItem Фізичне функціональне відновлення в ранній період після госпіталізації з приводу COVID-19: вплив гіпертонічної хвороби та модель прогнозування результату(2023-09) Honchar, Oleksii; Ashcheulova, Tetiana; Гончарь, Олексій Володимирович; Ащеулова, Тетяна ВадимівнаItem Spontaneous physical functional recovery after hospitalization for COVID-19: insights from a 1 month follow-up and a model to predict poor trajectory(2023-07) Honchar, Oleksii; Ashcheulova, Tetiana; Гончарь, Олексій Володимирович; Ащеулова, Тетяна ВадимівнаItem Heart rate turbulence and its relationship with other risk factors of sudden cardiac death(2020-05-22) Honchar, Oleksii; Гончарь, Олексій Володимирович; Гончарь, Алексей Владимирович; Титаренко, Н.В.; Копиця, М.П.; Юхновський, О.Ю.; Родіонова, Ю.В.; Кобець, А.В.; Кутя, І.М.; Біла, Н.В.; Tytarenko, N.; Kopytsya, Mykola; Yuchnovsky, O.; Rodionova, J.; Kobets, A.; Kutya, I.; Bila, N.