Role of nesfatin-1 in maintaining carbohydrate homeostasis in hypertensive patients

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Date

2016-11

Authors

Vizir, Maryna
Візір, Марина Олександрівна
Визир, Марина Александровна
Ковальова, Ольга Миколаївна
Ковалева, Ольга Николаевна
Kovalyova, Olga

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Publisher

V. N. Karazin Kharkiv National University

Abstract

The aim of this study is to analyze changes in the nesfatin-1 level in hypertensive patients depending on the carbohydrate profile parameters. 83 hypertensive patients aged 33 to 77 years were examined. Nesfatin-1 levels were determined by enzyme immunoassay method. Hypertensive patients have significantly higher levels of adipocytokine than healthy people. Results of data analyses may indicate a possible antihyperglycemic and insulinotropic effect of nesfatin-1 in hypertensive patients with normoglycemia or prediabetes. Confirmation of these processes requires a special study.

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Keywords

nesfatin-1, insulin, hypertension, prediabetes, polymorbidity

Citation

Vizir M. Role of nesfatin-1 in maintaining carbohydrate homeostasis in hypertensive patients / M. Vizir, O. Kovalyova // The Journal of V. N. Karazin Kharkiv National University. Series Medicine. – 2016. – № 32. – С. 33–36.

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