Наукові праці. Кафедра фізіології
Permanent URI for this collectionhttps://repo.knmu.edu.ua/handle/123456789/1394
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Item The ways of improvement the stress resilience(2024-12-03) Кармазіна, І.С.; Чернякова, О.Є.Stressors have a great impact on a person's mood, well-being, behavior and health. On the one hand, acute stress reactions can be adaptive, on the other hand, long-term exposure to stressors can disrupt health. The relationship between psychosocial stressors and the development of the disease is influenced by the nature and number of stressors, as well as individual stress resistance, i.e. resources for overcoming stress.Item Medical education of the future: transformation under the unfluence of artificial intelligence(2024-05-28) Marakushyn, Dmytro; Morozov, Oleksandr; Bondareva, Alla; Stetsenko, SvitlanaArtificial intelligence has the potential to accelerate the achievement of global education goals by reducing barriers to access to learning, automating management processes and optimizing methods to improve learning outcomes. The world of medical education is going through a period of rapid change caused by the rapid development of artificial intelligence.Item Beyond survival: distance learning as a lifeline for medical education in Ukraine during the war(2024-05-28) Marakushyn, Dmytro; Bondareva, Alla; Morozov, OleksandrThe war in Ukraine, which has been going on for the second year in a row, could not but affect all areas of life, including higher education. The most important task for universities is not only to ensure the continuity of education, but also to guarantee the safety of students.Item The role of unbalaneced diet in metabolic syndrom progression(2024-05-21) Karmazina, I.; Isaieva, I.; Kovalyov, M.; Pavlov, O.Adherence to unbalanced diet can cause the pancreatic beta-cells dysfunction leading to carbohydrates metabolism impairment and insulin resistance. The adaptation of an organism to the high content of lipids and carbohydrates in a diet is accompanied by early oxidative stress and changes in expression genes that regulate lipids metabolism promoting MS progression.Item Impact of stress on emotional health and cognitive function(2024) Marakushin, D.; Bulynina, O.; Isaieva, I.; Karmazina, I.; Maslova, N.Emotional stress can have both a positive effect, which is aimed at adaptation, and a negative one, which affects the higher integrative functions of the brain, and also leads to the development of numerous diseases. In this regard, the problem of establishing the influence of stress factors on the emotional state and cognitive function becomes relevant, which creates the prerequisites for a detailed analysis of the scientific data.Item Warm-up exercises as a crucial factor of preparation for physical activity: physiological reasoning(2024-05) Marakushyn, D.; Isaieva, I.; Karmazina, I.; Hromko, Ye.Physical activity can be challenging for the body, especially when performed suddenly and without proper preparation. To avoid the risk of injury and optimize a performance, athletes and trainers use warm-up exercises to prepare the body for activity. Proper increase of physiological indicators and providing safety as one of the most crucial points are primarily vital tasks of sports physiology. In our research, we summarized the physiological mechanisms underlying the body's preparation for physical activity and highlighted the importance of warm-up exercise. Warm-up exercise has a wide range of physiological benefits related to effects on many body systems like musculoskeletal, cardiovascular, respiratory and the whole body at all. The effectiveness of warm-up exercises is expressed in a quantitative increase in physiological indicators, which are pointed out in the article and explored from the physiological point of view.Item Study of the role of proinflammatory cytokines in the progression of diabetic nephropathy(2024) Alekseienko, R.; Rysovana, L.In the progression of diabetic nephropathy (DN), great importance is attached to immune factors, in particular, the cytokine system, which is a universal polymorphic regulatory network of mediators that control the proliferation and differentiation of cellular elements in hematopoietic, immune and other homeostatic systems. The role of proinflammatory cytokines in the development and progression of DN is almost unexplored, so the authors studied the role of proinflammatory cytokines in DN at different degrees of the functional state of the kidneys. Results of the presented studies indicate that pro-inflammatory cytokines play an important role in the progression of DN, contribute to the development of sclerotic processes in the kidneys. Indicators of IL-1α and TNF-α levels can be used as markers of progression of DN and criteria for the prognosis of this common and dangerous disease. The study of cytokines in DN can be useful for deepening knowledge of the mechanisms of pathogenesis, the development of criteria for its progression and prognosis, as well as to develop new approaches to the treatment of this common and dangerous complication of diabetes mellitus.Item Comparative myocardial oxygen consumption characteristics for the individuals with different types of functional asymmetry(2024-01) Bulynina, O.D.; Maslova, N.M.In the process of activities, changes are observed in the functional state of the body that are conditioned by the transition of physiological systems from a state of rest to that of stress and fatigue with subsequent recovery of those systems. The functional state of the cardiovascular system responding most promptly to muscle efforts and limiting the body's capacity to work can serve as a reliable indicator of the level of adaptive reactions to emerging internal and external effects under intense physical exertion.Item Aggressive parenting: social, medical and legal aspects(2024-01) Isaieva, Inna; Isaiev, Arsen; Korobtsova, Nataliia; Nadon, Victoriia; Puchkovska, IrynaAggressive parenting is considered as style using threats or different kinds of punishments such as psychological or physical to keep a child under control or pressure to obey. However, the standardized definition of aggressive parenting doesn’t exist and most of interpretations are focused on physical aggression which refers to actions with intention of causing physical pain or injury.Item Expression features of T-lymphocytes, B-lymphocytes and macrophages in the post-traumatic regenerate of the mandible rats under conditions of filling a bone defects with hydroxyaparite-containing osteotropic material and thymalin injecting the surrounding soft tissues(2024-04) Boiko, Andrii; Malanchuk, Vladislav; Myroshnychenko, Mykhailo; Markovska, Olena; Shapkin, Anton; Marakushin, DmytroThe purpose of the study was to determine the features of the expression of T-lymphocytes, B-lymphocytes, macrophages in the post-traumatic regenerate of the mandible rats under conditions of filling a bone defect with hydroxyapatite-containing osteotropic material and thymalin injecting the surroundingsoft tissues.